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Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Yamada, Ken; Hariharan, Vignesh Narayan; Caiazzi, Jillian; Miller, Rachael; Furguson, Chantal; Sapp, Ellen; Fakih, Hassan; Tan, Qi; Yamada, Nozomi; Furgal, Raymond C; Paquette, Joseph; Bramato, Brianna; McHugh, Nicholas; Summers, Ashley; Lochmann, Clemens; Godinho, Bruno M D C; Hildebrand, Samuel; Echeverria, Dimas; Hassler, Matthew R; Alterman, Julia F; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia.
  • Yamada K; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Hariharan VN; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Caiazzi J; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Miller R; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Furguson C; Department of Medicine, University of Massachusetts Chan Medical School; Charlestown, Massachusetts, United State.
  • Sapp E; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Fakih H; Department of Medicine, University of Massachusetts Chan Medical School; Charlestown, Massachusetts, United State.
  • Tan Q; Department of Neurology, Harvard Medical School and Mass General Institute for Neurodegenerative Disease, Charlestown, Massachusetts, United State.
  • Yamada N; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Furgal RC; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Paquette J; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Bramato B; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • McHugh N; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Summers A; Department of Medicine, University of Massachusetts Chan Medical School; Charlestown, Massachusetts, United State.
  • Lochmann C; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Godinho BMDC; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Hildebrand S; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Echeverria D; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Hassler MR; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Alterman JF; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • DiFiglia M; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Aronin N; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
  • Khvorova A; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, United States.
bioRxiv ; 2023 May 26.
Article en En | MEDLINE | ID: mdl-37292886
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article