Advances in small molecule selective ligands for heteromeric nicotinic acetylcholine receptors.

Matera, Carlo; Papotto, Claudio; Dallanoce, Clelia; De Amici, Marco

Matera, Carlo; Papotto, Claudio; Dallanoce, Clelia; De Amici, Marco.

Matera C; Department of Pharmaceutical Sciences, Medicinal Chemistry Section "Pietro Pratesi", University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Papotto C; Department of Pharmaceutical Sciences, Medicinal Chemistry Section "Pietro Pratesi", University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
Dallanoce C; Department of Pharmaceutical Sciences, Medicinal Chemistry Section "Pietro Pratesi", University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy.
De Amici M; Department of Pharmaceutical Sciences, Medicinal Chemistry Section "Pietro Pratesi", University of Milan, Via Luigi Mangiagalli 25, 20133 Milan, Italy. Electronic address: marco.deamici@unimi.it.

Pharmacol Res ; 194: 106813, 2023 08.

Article en En | MEDLINE | ID: mdl-37302724

Asunto(s)

Receptores Nicotínicos; Receptores Nicotínicos/metabolismo; Ligandos; Regulación Alostérica; Neuronas/metabolismo; Transmisión Sináptica; Nicotina; Antagonistas Nicotínicos/metabolismo; Antagonistas Nicotínicos/farmacología

Palabras clave

Allosteric nicotinic modulators; Dual-acting nicotinic ligands; Heteromeric nAChRs; Light-regulated nicotinic ligands; Nicotinic acetylcholine receptors (nAChRs); Nicotinic radiopharmaceuticals; Orthosteric nicotinic agonists; Orthosteric nicotinic antagonists

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Nicotínicos Idioma: En Año: 2023 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Nicotínicos Idioma: En Año: 2023 Tipo del documento: Article