Mixtures of per- and poly-fluoroalkyl substances (PFAS) reduce the in vitro activation of human T cells and basophils.

Maddalon, Ambra; Pierzchalski, Arkadiusz; Kretschmer, Tobias; Bauer, Mario; Zenclussen, Ana C; Marinovich, Marina; Corsini, Emanuela; Herberth, Gunda

Maddalon, Ambra; Pierzchalski, Arkadiusz; Kretschmer, Tobias; Bauer, Mario; Zenclussen, Ana C; Marinovich, Marina; Corsini, Emanuela; Herberth, Gunda.

Maddalon A; Laboratory of Toxicology, Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy.
Pierzchalski A; Department of Environmental Immunology, Helmholtz Centre for Environmental Research -UFZ, Leipzig, Germany.
Kretschmer T; Department of Environmental Immunology, Helmholtz Centre for Environmental Research -UFZ, Leipzig, Germany.
Bauer M; Department of Environmental Immunology, Helmholtz Centre for Environmental Research -UFZ, Leipzig, Germany.
Zenclussen AC; Department of Environmental Immunology, Helmholtz Centre for Environmental Research -UFZ, Leipzig, Germany; Perinatal Immunology Research Group, Medical Faculty, Saxonian Incubator for Clinical Translation (SIKT), University of Leipzig, Leipzig, Germany.
Marinovich M; Laboratory of Toxicology, Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy.
Corsini E; Laboratory of Toxicology, Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy.
Herberth G; Department of Environmental Immunology, Helmholtz Centre for Environmental Research -UFZ, Leipzig, Germany. Electronic address: gunda.herberth@ufz.de.

Chemosphere ; 336: 139204, 2023 Sep.

Article en En | MEDLINE | ID: mdl-37315852

Asunto(s)

Fluorocarburos; Células T Invariantes Asociadas a Mucosa; Humanos; Basófilos; Células T Invariantes Asociadas a Mucosa/metabolismo; Citometría de Flujo; Fluorocarburos/toxicidad; Fluorocarburos/metabolismo; Miembro 15 de la Superfamilia de Ligandos de Factores de Necrosis Tumoral/metabolismo

Palabras clave

Basophils; Immunotoxicity; MAIT cells; Mixtures; PFAS; T lymphocytes

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fluorocarburos / Células T Invariantes Asociadas a Mucosa Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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