Different pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania.

Pacholko, Anthony G; Bekar, Lane K

Pacholko, Anthony G; Bekar, Lane K.

Pacholko AG; Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada. Electronic address: anthony.pacholko@gmail.com.
Bekar LK; Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada. Electronic address: lane.bekar@usask.ca.

J Psychiatr Res ; 164: 192-201, 2023 08.

Article en En | MEDLINE | ID: mdl-37356352

Asunto(s)

Trastorno Bipolar; Carbonato de Litio; Masculino; Femenino; Ratones; Animales; Carbonato de Litio/efectos adversos; Manía/inducido químicamente; Manía/tratamiento farmacológico; Trastorno Bipolar/tratamiento farmacológico; Litio/uso terapéutico; Anfetamina/uso terapéutico; Modelos Animales de Enfermedad; Antimaníacos/farmacología

Palabras clave

Amphetamine-induced hyperlocomotion; Bipolar disorder; Lithium; Mania; Orotate

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastorno Bipolar / Carbonato de Litio Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

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