Serological Prevalence of Crimean-Congo Hemorrhagic Fever Virus Infection in Small Ruminants and Cattle in The Gambia.
Pathogens
; 12(6)2023 May 23.
Article
en En
| MEDLINE
| ID: mdl-37375439
ABSTRACT
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed tickborne zoonotic agent that infects a variety of host species. There is a lack of information on the true geographic distribution of the prevalence and risk of CCHFV in West Africa. A countrywide cross-sectional study involving 1413 extensively managed indigenous small ruminants and cattle at livestock sales markets and in village herds, respectively, was carried out in The Gambia. In sheep, an overall anti-CCHFV antibody prevalence of 18.9% (95% CI 15.5-22.8%), goats 9.0% (95% CI 6.7-11.7%), and cattle 59.9% (95% CI 54.9-64.7%) was detected. Significant variation (p < 0.05) in the prevalence of anti-CCHFV antibodies at sites in the five administrative regions (sheep 4.8-25.9%; goats 1.8-17.1%) and three agroecological zones (sheep 8.9-32.9%; goats 4.1-18.0%) was also observed. Comparatively, higher anti-CCHFV antibody prevalence was detected in cattle (33.3-84.0%) compared to small ruminants (1.8-8.1%). This study represents the first countrywide investigation of the seroprevalence of CCHFV in The Gambia, and the results suggest potential circulation and endemicity of the virus in the country. These data provide critical information vital to the development of informed policies for the surveillance, diagnosis, and control of CCFHV infection in The Gambia and the region.
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MEDLINE
Tipo de estudio:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Idioma:
En
Año:
2023
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Article