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Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.
Mastini, Cristina; Campisi, Marco; Patrucco, Enrico; Mura, Giulia; Ferreira, Antonio; Costa, Carlotta; Ambrogio, Chiara; Germena, Giulia; Martinengo, Cinzia; Peola, Silvia; Mota, Ines; Vissio, Elena; Molinaro, Luca; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele; Prokoph, Nina; Tabbò, Fabrizio; Shoji, Brent; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D; Cuesta-Mateos, Carlos; D'Aliberti, Deborah; Mologni, Luca; Piazza, Rocco; Gambacorti-Passerini, Carlo; Inghirami, Giorgio G; Chiono, Valeria; Kamm, Roger D; Hirsch, Emilio; Koch, Raphael; Weinstock, David M; Aster, Jon C; Voena, Claudia; Chiarle, Roberto.
  • Mastini C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Campisi M; Dana Farber Cancer Institute, Boston, MA 02115, USA.
  • Patrucco E; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Mura G; Department of Mechanical and Aerospace Engineering, Politecnico of Torino, Torino 10129, Italy.
  • Ferreira A; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Costa C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Ambrogio C; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston MA 02115, USA.
  • Germena G; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Martinengo C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Peola S; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Mota I; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Vissio E; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Molinaro L; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Arigoni M; Department of Oncology, University of Torino, Orbassano, Torino 10043, Italy.
  • Olivero M; Department of Medical Science, University of Torino, Torino 10126, Italy.
  • Calogero R; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Prokoph N; Department of Oncology, University of Torino, Orbassano, Torino 10043, Italy.
  • Tabbò F; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino 10060, Italy.
  • Shoji B; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino 10126, Italy.
  • Brugieres L; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
  • Geoerger B; Department of Pathology, Cornell University, New York NY 10121, USA.
  • Turner SD; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston MA 02115, USA.
  • Cuesta-Mateos C; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Paris-Saclay University, Villejuif 94805, France.
  • D'Aliberti D; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Paris-Saclay University, Villejuif 94805, France.
  • Mologni L; Université Paris-Saclay, INSERM U1015, Villejuif 94805, France.
  • Piazza R; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
  • Gambacorti-Passerini C; Faculty of Medicine, Masaryk University, Brno 601 77, Czech Republic.
  • Inghirami GG; Department of Pre-Clinical Development, Catapult Therapeutics B.V., 8243 RC, Lelystad, Netherlands.
  • Chiono V; Department of Medicine and Surgery, University of Milan-Bicocca, Monza 20900, Italy.
  • Kamm RD; Department of Medicine and Surgery, University of Milan-Bicocca, Monza 20900, Italy.
  • Hirsch E; Department of Medicine and Surgery, University of Milan-Bicocca, Monza 20900, Italy.
  • Koch R; Department of Medicine and Surgery, University of Milan-Bicocca, Monza 20900, Italy.
  • Weinstock DM; Department of Pathology, Cornell University, New York NY 10121, USA.
  • Aster JC; Department of Mechanical and Aerospace Engineering, Politecnico of Torino, Torino 10129, Italy.
  • Voena C; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chiarle R; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sci Transl Med ; 15(702): eabo3826, 2023 06 28.
Article en En | MEDLINE | ID: mdl-37379367
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfoma Anaplásico de Células Grandes / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfoma Anaplásico de Células Grandes / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article