CYP2J deficiency leads to cardiac injury and presents dual regulatory effects on cardiac function in rats.

Zhang, Yanfang; Lu, Jian; Huang, Shengbo; Zhang, Yuanjin; Liu, Jie; Xu, Yuan; Yao, Bingyi; Wang, Xin

Zhang, Yanfang; Lu, Jian; Huang, Shengbo; Zhang, Yuanjin; Liu, Jie; Xu, Yuan; Yao, Bingyi; Wang, Xin.

Zhang Y; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Lu J; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Huang S; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Zhang Y; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Liu J; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Xu Y; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China.
Yao B; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China. Electronic address: 13816852233@163.com.
Wang X; Changning Maternity and Infant Health Hospital and School of Life Sciences, Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai, China. Electronic address: xwang@bio.ecnu.edu.cn.

Toxicol Appl Pharmacol ; 473: 116610, 2023 08 15.

Article en En | MEDLINE | ID: mdl-37385478

Asunto(s)

Citocromo P-450 CYP2J2; Lesiones Cardíacas; Ratas; Animales; Ácido 8,11,14-Eicosatrienoico/metabolismo; Ácido 8,11,14-Eicosatrienoico/farmacología; Células Endoteliales/metabolismo; Sistema Enzimático del Citocromo P-450/genética; Sistema Enzimático del Citocromo P-450/metabolismo; Miocitos Cardíacos; Lesiones Cardíacas/metabolismo

Palabras clave

CYP2J; Cardiac function; Cardiovascular disease; Epoxyeicosatrienoic acids (EETs); Metabolic regulation

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citocromo P-450 CYP2J2 / Lesiones Cardíacas Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citocromo P-450 CYP2J2 / Lesiones Cardíacas Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article