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Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma.
Fall, Amary; Campodónico, Victoria L; Howard, Craig; Gallagher, Nicholas; Bailey, Gabrielle; Kajon, Adriana E; Mostafa, Heba H.
  • Fall A; Hopkins Medicine, Department of Pathology, Medical Microbiology, Baltimore, MD, USA.
  • Campodónico VL; Hopkins Medicine, Department of Pathology, Medical Microbiology, Baltimore, MD, USA.
  • Howard C; Department of Pathology, Medical Microbiology, Johns Hopkins Hospital, Baltimore, MD, USA.
  • Gallagher N; Hopkins Medicine, Department of Pathology, Medical Microbiology, Baltimore, MD, USA.
  • Bailey G; Hopkins Medicine, Department of Pathology, Medical Microbiology, Baltimore, MD, USA.
  • Kajon AE; Lovelace Biomedical Research Institute, Albuquerque, NM, USA.
  • Mostafa HH; Hopkins Medicine, Department of Pathology, Medical Microbiology, Baltimore, MD, USA. hmostaf2@jhmi.edu.
Virol J ; 20(1): 141, 2023 Jul 06.
Article en En | MEDLINE | ID: mdl-37415207
ABSTRACT
Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high-grade diffuse large B-cell lymphoma on chemotherapy was diagnosed with disseminated adenovirus infection. HAdV DNA was quantified in stool, plasma, and urine with viral loads of 7, 4, and 3 log10 copies/mL, respectively. The patient's course was rapidly progressive and he passed away 2 days after initiation of antiviral therapy. The patient's infecting virus was characterized as HAdV-F41 by whole genome sequencing.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones por Adenovirus Humanos / Adenovirus Humanos / Linfoma de Células B / Infecciones por Adenoviridae Límite: Adult / Humans / Male Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones por Adenovirus Humanos / Adenovirus Humanos / Linfoma de Células B / Infecciones por Adenoviridae Límite: Adult / Humans / Male Idioma: En Año: 2023 Tipo del documento: Article