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Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis.
Shiau, Carina; Cao, Jingyi; Gregory, Mark T; Gong, Dennis; Yin, Xunqin; Cho, Jae-Won; Wang, Peter L; Su, Jennifer; Wang, Steven; Reeves, Jason W; Kim, Tae Kyung; Kim, Youngmi; Guo, Jimmy A; Lester, Nicole A; Schurman, Nathan; Barth, Jamie L; Weissleder, Ralph; Jacks, Tyler; Qadan, Motaz; Hong, Theodore S; Wo, Jennifer Y; Roberts, Hannah; Beechem, Joseph M; Castillo, Carlos Fernandez-Del; Mino-Kenudson, Mari; Ting, David T; Hemberg, Martin; Hwang, William L.
  • Shiau C; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Cao J; Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Gregory MT; NanoString Technologies, Seattle, WA, USA.
  • Gong D; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Yin X; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Cho JW; Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Wang PL; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Su J; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Wang S; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Reeves JW; NanoString Technologies, Seattle, WA, USA.
  • Kim TK; NanoString Technologies, Seattle, WA, USA.
  • Kim Y; NanoString Technologies, Seattle, WA, USA.
  • Guo JA; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Lester NA; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
  • Schurman N; NanoString Technologies, Seattle, WA, USA.
  • Barth JL; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Weissleder R; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Jacks T; Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Qadan M; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Hong TS; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Wo JY; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Roberts H; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Beechem JM; NanoString Technologies, Seattle, WA, USA.
  • Castillo CF; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Mino-Kenudson M; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Ting DT; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Medical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Hemberg M; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Hwang WL; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School,
bioRxiv ; 2023 Jun 29.
Article en En | MEDLINE | ID: mdl-37425692

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Año: 2023 Tipo del documento: Article