Analysis of the Peritumoral Tissue Unveils Cellular Changes Associated with a High Risk of Recurrence.
Cancers (Basel)
; 15(13)2023 Jun 30.
Article
en En
| MEDLINE
| ID: mdl-37444560
ABSTRACT
BACKGROUND:
The management of soft-tissue sarcoma (STS) relies on a multidisciplinary approach involving specialized oncological surgery combined with other adjuvant therapies to achieve optimal local disease control. Purpose andResults:
Genomic and transcriptomic pseudocapsules of 20 prospective sarcomas were analyzed and revealed to be correlated with a higher risk of recurrence after surgery.CONCLUSIONS:
A peritumoral environment that has been remodeled and infiltrated by M2 macrophages, and is less expressive of healthy tissue, would pose a significant risk of relapse and require more aggressive treatment strategies.
Texto completo:
1
Banco de datos:
MEDLINE
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Año:
2023
Tipo del documento:
Article