Your browser doesn't support javascript.
loading
Analysis of the Peritumoral Tissue Unveils Cellular Changes Associated with a High Risk of Recurrence.
Michot, Audrey; Lagarde, Pauline; Lesluyes, Tom; Darbo, Elodie; Neuville, Agnès; Baud, Jessica; Perot, Gaëlle; Bonomo, Iris; Maire, Mathilde; Michot, Maxime; Coindre, Jean-Michel; Le Loarer, François; Chibon, Frédéric.
  • Michot A; Bordeaux Institute of Oncology, BRIC U1312, INSERM, 33000 Bordeaux, France.
  • Lagarde P; Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 33076 Bordeaux, France.
  • Lesluyes T; Department of Biopathology, Bergonié Institute, Université Victor Segalen Site Carreire, Bordeaux 2, 33076 Bordeaux, France.
  • Darbo E; Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 33076 Bordeaux, France.
  • Neuville A; Department of Biopathology, Bergonié Institute, Université Victor Segalen Site Carreire, Bordeaux 2, 33076 Bordeaux, France.
  • Baud J; Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 33076 Bordeaux, France.
  • Perot G; Bordeaux Institute of Oncology, BRIC U1312, INSERM, 33000 Bordeaux, France.
  • Bonomo I; Department of Biopathology, Bergonié Institute, Université Victor Segalen Site Carreire, Bordeaux 2, 33076 Bordeaux, France.
  • Maire M; Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 33076 Bordeaux, France.
  • Michot M; Bordeaux Institute of Oncology, BRIC U1312, INSERM, 33000 Bordeaux, France.
  • Coindre JM; OncoSarc, INSERM U1037, Cancer Research Center in Toulouse (CRCT), 31000 Toulouse, France.
  • Le Loarer F; Department of Pathology, Institut Claudius Régaud, IUCT-Oncopole, 31000 Toulouse, France.
  • Chibon F; Institut Bergonié, Centre de Lutte Contre le Cancer de Bordeaux, 33076 Bordeaux, France.
Cancers (Basel) ; 15(13)2023 Jun 30.
Article en En | MEDLINE | ID: mdl-37444560
ABSTRACT

BACKGROUND:

The management of soft-tissue sarcoma (STS) relies on a multidisciplinary approach involving specialized oncological surgery combined with other adjuvant therapies to achieve optimal local disease control. Purpose and

Results:

Genomic and transcriptomic pseudocapsules of 20 prospective sarcomas were analyzed and revealed to be correlated with a higher risk of recurrence after surgery.

CONCLUSIONS:

A peritumoral environment that has been remodeled and infiltrated by M2 macrophages, and is less expressive of healthy tissue, would pose a significant risk of relapse and require more aggressive treatment strategies.
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Año: 2023 Tipo del documento: Article