AMPK boosts ADAM10 shedding activity in human aortic endothelial cells by promoting Rab14-dependent ADAM10 cell surface translocation.

Baek, Chung Hee; Kim, Hyosang; Moon, Soo Young; Yang, Won Seok

Baek, Chung Hee; Kim, Hyosang; Moon, Soo Young; Yang, Won Seok.

Baek CH; Division of Nephrology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kim H; Division of Nephrology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Moon SY; Asan Institute for Life Sciences, Seoul, Republic of Korea.
Yang WS; Division of Nephrology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address: wsyang@amc.seoul.kr.

Biochem Biophys Res Commun ; 675: 54-60, 2023 10 01.

Article en En | MEDLINE | ID: mdl-37451218

Asunto(s)

Proteínas Quinasas Activadas por AMP; Células Endoteliales; Humanos; Células Endoteliales/metabolismo; Proteínas Quinasas Activadas por AMP/metabolismo; Proteína ADAM10/metabolismo; Membrana Celular/metabolismo; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/metabolismo; Receptor para Productos Finales de Glicación Avanzada/metabolismo; Secretasas de la Proteína Precursora del Amiloide/metabolismo; Proteínas de la Membrana/metabolismo; Proteínas de Unión al GTP rab/metabolismo

Palabras clave

A disintegrin and metalloprotease 10; AMP-activated protein kinase; Cell surface trafficking; Rab14; Receptor for advanced glycation end products

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Endoteliales / Proteínas Quinasas Activadas por AMP Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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