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MAdCAM-1: a newly identified microbial 'gut check' for T cells.
Chelvanambi, Manoj; Wargo, Jennifer A.
  • Chelvanambi M; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
  • Wargo JA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address: jwargo@mdanderson.org.
Trends Immunol ; 44(8): 568-570, 2023 08.
Article en En | MEDLINE | ID: mdl-37451906
ABSTRACT
The gut microbiome influences the response, resistance, and toxicity of cancer immunotherapy, but the underlying mechanisms remain unknown. Fidelle et al. identify intestinal MAdCAM-1 as a mechanistic target through which gut dysbiosis blunts antitumor immunity, with opportunities for putative therapeutic intervention.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Microbioma Gastrointestinal Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Microbioma Gastrointestinal Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article