MAdCAM-1: a newly identified microbial 'gut check' for T cells.
Trends Immunol
; 44(8): 568-570, 2023 08.
Article
en En
| MEDLINE
| ID: mdl-37451906
ABSTRACT
The gut microbiome influences the response, resistance, and toxicity of cancer immunotherapy, but the underlying mechanisms remain unknown. Fidelle et al. identify intestinal MAdCAM-1 as a mechanistic target through which gut dysbiosis blunts antitumor immunity, with opportunities for putative therapeutic intervention.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos T
/
Microbioma Gastrointestinal
Límite:
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article