Severe Congenital Heart Defects and Cerebral Palsy.
J Pediatr
; 262: 113617, 2023 11.
Article
en En
| MEDLINE
| ID: mdl-37473991
ABSTRACT
OBJECTIVE:
To report the prevalence of cerebral palsy (CP) in children with severe congenital heart defects (sCHD) and the outcome/severity of the CP.METHODS:
Population-based, data linkage study between CP and congenital anomaly registers in Europe and Australia. The EUROCAT definition of severe CHD (sCHD) was used. Linked data from 4 regions in Europe and 2 in Australia were included. All children born in the regions from 1991 through 2009 diagnosed with CP and/or sCHD were included. Linkage was completed locally. Deidentified linked data were pooled for analyses.RESULTS:
The study sample included 4989 children with CP and 3684 children with sCHD. The total number of livebirths in the population was 1â734â612. The prevalence of CP was 2.9 per 1000 births (95% CI, 2.8-3.0) and the prevalence of sCHD was 2.1 per 1000 births (95% CI, 2.1-2.2). Of children with sCHD, 1.5% (n = 57) had a diagnosis of CP, of which 35 (61%) children had prenatally or perinatally acquired CP (resulting from a brain injury at ≤28 days of life) and 22 (39%) children had a postneonatal cause (a brain injury between 28 days and 2 years). Children with CP and sCHD more often had unilateral spastic CP and more intellectual impairments than children with CP without congenital anomalies.CONCLUSIONS:
In high-income countries, the proportion of children with CP is much higher in children with sCHD than in the background population. The severity of disease in children with CP and sCHD is milder compared with children with CP without congenital anomalies.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Lesiones Encefálicas
/
Parálisis Cerebral
/
Cardiopatías Congénitas
Tipo de estudio:
Risk_factors_studies
Límite:
Child
/
Humans
País como asunto:
Europa
Idioma:
En
Año:
2023
Tipo del documento:
Article