WallFlex® and Evolution® Duodenal Stents Have Similar Efficacy but Different Safety for Malignant Gastric Outlet Obstruction.
Dig Dis Sci
; 68(9): 3688-3693, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37477765
ABSTRACT
BACKGROUND:
The WallFlex® and Evolution® stents are the most widely used duodenal stents, but no study has compared them.AIMS:
We aimed to compare the efficacy and safety of WallFlex® and Evolution® stents for malignant gastric outlet obstruction.METHODS:
We included all consecutive patients who were treated for malignant gastric outlet obstruction with WallFlex® or Evolution® self-expandable metal uncovered duodenal stents between 2013 and 2020. Multivariable Cox models were performed to assess duodenal stent failure, as defined by gastric outlet obstruction necessitating another duodenal stent.RESULTS:
We included 129 patients 74 received a WallFlex® stent and 55 received an Evolution® stent. The non-failure rate was of 68% (95%CI 55-84) and 65% (95%CI 50-84) at 6 months and of 48% (95%CI 32-73) and 45% (95%CI 27-74) at 1 year, with the WallFlex® and Evolution® stents, respectively. The median time to duodenal stent failure was 10.5 months in the WallFlex® group and 9.3 months in the Evolution® group. The type of duodenal stent was not associated with duodenal stent failure (p logrank = 0.43, adjusted hazard ratio 1.55; 95%CI 0.77-3.14). The overall survival was similar between the two groups (p logrank = 0.92). Three patients had complications due to Evolution® stents; it consisted in dismantled stents that led to hemorrhage in one patient.CONCLUSIONS:
WallFlex® and Evolution® duodenal stents had similar efficacy for malignant gastric outlet obstruction. There were more adverse events with Evolution® stents.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Obstrucción de la Salida Gástrica
/
Obstrucción Duodenal
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article