Is Continuous Positive Airway Pressure a Valid Alternative to Sildenafil in Treating Sexual Dysfunction among OSA Patients? A Systematic Review and Meta-Analysis.
Medicina (Kaunas)
; 59(7)2023 Jul 17.
Article
en En
| MEDLINE
| ID: mdl-37512129
ABSTRACT
Background and Objectives:
This study aimed to assess the comparative effectiveness of continuous positive airway pressure (CPAP) therapy and sildenafil pharmacological therapy in improving sexual function among patients with obstructive sleep apnea (OSA) and erectile dysfunction (ED). Materials andmethods:
Population Patients affected by OSA and ED; Intervention CPAP therapy vs. Comparison Sildenafil pharmacological therapy;Outcomes:
Improvement in erectile function, as measured by the International Index of Erectile Function 5 (IIEF-5) scoring system; Time A systematic review of the literature from the past 20 years; StudyDesign:
Observational studies comparing erectile function improvements after OSA treatment.Results:
A total of eight papers were included in the qualitative summary, involving four hundred fifty-seven patients with ED and OSA. Erectile function improvements were observed in both treatment groups. After sildenafil and CPAP treatment, the mean IIEF-5 domain scores were 37.7 and 27.3, respectively (p < 0.001). Sildenafil 100 mg demonstrated a higher therapeutic impact compared to CPAP treatment.Conclusions:
CPAP therapy significantly improved sexual parameters in most studies for OSA patients with ED. The findings suggest that CPAP therapy effectively alleviates erectile dysfunction symptoms, resulting in improved sexual performance in OSA patients. The comparison of the two treatments indicates that sildenafil has a more substantial therapeutic impact on erectile function than CPAP therapy; however, a combined treatment will provide a cumulative effect.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Disfunciones Sexuales Fisiológicas
/
Apnea Obstructiva del Sueño
/
Disfunción Eréctil
Tipo de estudio:
Observational_studies
/
Qualitative_research
/
Systematic_reviews
Límite:
Humans
/
Male
Idioma:
En
Año:
2023
Tipo del documento:
Article