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SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates.
Bader, Stefanie M; Cooney, James P; Sheerin, Dylan; Taiaroa, George; Harty, Leigh; Davidson, Kathryn C; Mackiewicz, Liana; Dayton, Merle; Wilcox, Stephen; Whitehead, Lachlan; Rogers, Kelly L; Georgy, Smitha Rose; Coussens, Anna K; Grimley, Samantha L; Corbin, Vincent; Pitt, Miranda; Coin, Lachlan; Pickering, Raelene; Thomas, Merlin; Allison, Cody C; McAuley, Julie; Purcell, Damian F J; Doerflinger, Marcel; Pellegrini, Marc.
  • Bader SM; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Cooney JP; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Sheerin D; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Taiaroa G; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Harty L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Davidson KC; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Mackiewicz L; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
  • Dayton M; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
  • Wilcox S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Whitehead L; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Rogers KL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Georgy SR; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Coussens AK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Grimley SL; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Corbin V; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Pitt M; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Coin L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • Pickering R; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Thomas M; Anatomic Pathology, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Melbourne, VIC 3030, Australia.
  • Allison CC; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.
  • McAuley J; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
  • Purcell DFJ; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
  • Doerflinger M; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
  • Pellegrini M; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
Proc Natl Acad Sci U S A ; 120(32): e2301689120, 2023 08 08.
Article en En | MEDLINE | ID: mdl-37523564
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Adult / Aged / Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Adult / Aged / Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article