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Structural insights into selective small molecule activation of PKG1α.
Metwally, Essam; Mak, Victor; Soriano, Aileen; Zebisch, Matthias; Silvestre, H Leonardo; McEwan, Paul A; Ermakov, Grigori; Beaumont, Maribel; Tawa, Paul; Barker, John J; Yen, Rose; Patel, Akash; Lim, Yeon-Hee; Healy, David; Hanisak, Jennifer; Cheng, Alan C; Greshock, Tom; Fischmann, Thierry O.
  • Metwally E; Modeling and Informatics, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA. essam.metwally@merck.com.
  • Mak V; Discovery Chemistry, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Soriano A; Quantitative Biosciences, MRL, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Zebisch M; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RZ, UK.
  • Silvestre HL; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RZ, UK.
  • McEwan PA; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RZ, UK.
  • Ermakov G; Discovery Bioanalytics, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Beaumont M; Discovery Bioanalytics, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Tawa P; Quantitative Biosciences, MRL, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Barker JJ; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RZ, UK.
  • Yen R; Discovery Chemistry, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Patel A; Discovery Chemistry, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Lim YH; Discovery Chemistry, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Healy D; Discovery Biology, MRL, Merck & Co., Inc., Boston, MA, USA.
  • Hanisak J; Discovery Chemistry, MRL, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Cheng AC; Modeling and Informatics, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Greshock T; Discovery Chemistry, MRL, Merck & Co., Inc., 213 E. Grand Avenue, South San Francisco, CA, USA.
  • Fischmann TO; Protein and Structural Chemistry, MRL, Merck & Co., Inc., Kenilworth, NJ, USA. thierry.fischmann@merck.com.
Commun Biol ; 6(1): 798, 2023 07 31.
Article en En | MEDLINE | ID: mdl-37524852
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína Quinasa Dependiente de GMP Cíclico Tipo I Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína Quinasa Dependiente de GMP Cíclico Tipo I Idioma: En Año: 2023 Tipo del documento: Article