Early impact of COVID-19 vaccination on older populations in four countries of the Americas, 2021.
Rev Panam Salud Publica
; 47: e122, 2023.
Article
en En
| MEDLINE
| ID: mdl-37564919
ABSTRACT
Objective:
To estimate the early impact of coronavirus disease 2019 (COVID-19) vaccination on cases in older populations in four countries (Chile, Colombia, Guatemala, and the United States of America), and on deaths in Chile and Guatemala.Methods:
Data were obtained from national databases of confirmed COVID-19 cases and deaths and vaccinations between 1 July 2020 and 31 August 2021. In each country, pre- and post-vaccination incidence ratios were calculated for COVID-19 cases and deaths in prioritized groups (50-59, 60-69, and ≥70 years) compared with those in the reference group (<50 years). Vaccination effect was calculated as the percentage change in incidence ratios between pre- and post-vaccination periods.Results:
The ratio of COVID-19 cases in those aged ≥50 years to those aged <50 years decreased significantly after vaccine implementation by 9.8% (95% CI 9.5 to 10.1%) in Chile, 22.5% (95% CI 22.0 to 23.1%) in Colombia, 20.8% (95% CI 20.6 to 21.1%) in Guatemala, and 7.8% (95% CI 7.6 to 7.9%) in the USA. Reductions in the ratio were highest in adults aged ≥70 years. The effect of vaccination on deaths, with time lags incorporated, was highest in the age group ≥70 years in both Chile and Guatemala 14.4% (95% CI 11.4 to 17.4%) and 37.3% (95% CI 30.9 to 43.7%), respectively.Conclusions:
COVID-19 vaccination significantly reduced morbidity in the early post-vaccination period in targeted groups. In the context of a global pandemic with limited vaccine availability, prioritization strategies are important to reduce the burden of disease in high-risk age groups.
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Banco de datos:
MEDLINE
Idioma:
En
Año:
2023
Tipo del documento:
Article