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HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation.
Xiao, Yufeng; Hale, Seth; Awasthee, Nikee; Meng, Chengcheng; Zhang, Xuan; Liu, Yi; Ding, Haocheng; Huo, Zhiguang; Lv, Dongwen; Zhang, Weizhou; He, Mei; Zheng, Guangrong; Liao, Daiqing.
  • Xiao Y; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
  • Hale S; Department of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Awasthee N; Department of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Meng C; Department of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Zhang X; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
  • Liu Y; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
  • Ding H; Department of Biostatistics, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Huo Z; Department of Biostatistics, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Lv D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
  • Zhang W; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA; UF Health Cancer Center, University of Florida, Gainesville, FL 32610, USA.
  • He M; Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA; UF Health Cancer Center, University of Florida, Gainesville, FL 32610, USA.
  • Zheng G; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA; UF Health Cancer Center, University of Florida, Gainesville, FL 32610, USA. Electronic address: zhengg@cop.ufl.edu.
  • Liao D; Department of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA; UF Health Cancer Center, University of Florida, Gainesville, FL 32610, USA. Electronic address: dliao@ufl.edu.
Cell Chem Biol ; 30(11): 1421-1435.e12, 2023 11 16.
Article en En | MEDLINE | ID: mdl-37572669
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Inhibidores de Histona Desacetilasas Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Inhibidores de Histona Desacetilasas Idioma: En Año: 2023 Tipo del documento: Article