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Development of novel HEPT analogs featuring significantly improved anti-resistance potency against HIV-1 through chemical space exploration of the tolerant region I.
Zhou, Ruo-Lan; Pannecouque, Christophe; De Clercq, Erik; Wang, Shuai; Chen, Fen-Er.
  • Zhou RL; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of C∼hemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China; Institute of Pharmaceutical Science and Technology, Zheji
  • Pannecouque C; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • De Clercq E; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Wang S; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of C∼hemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China. Electronic address: shuaiwang@fudan.edu.cn.
  • Chen FE; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of C∼hemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China; Institute of Pharmaceutical Science and Technology, Zheji
Bioorg Chem ; 140: 106783, 2023 11.
Article en En | MEDLINE | ID: mdl-37595396

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vuelo Espacial / VIH-1 Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vuelo Espacial / VIH-1 Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article