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The net electrostatic potential and hydration of ABCG2 affect substrate transport.
Gose, Tomoka; Aitken, Heather M; Wang, Yao; Lynch, John; Rampersaud, Evadnie; Fukuda, Yu; Wills, Medb; Baril, Stefanie A; Ford, Robert C; Shelat, Anang; Mara, Megan L O'; Schuetz, John D.
  • Gose T; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Aitken HM; Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Australia, Cnr College Rd & Cooper Rd, St Lucia, QLD, 4072, Australia.
  • Wang Y; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Lynch J; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Rampersaud E; Center for Applied Bioinformatics, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Fukuda Y; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Wills M; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Baril SA; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Ford RC; School of Biological Sciences, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
  • Shelat A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Mara MLO; Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Australia, Cnr College Rd & Cooper Rd, St Lucia, QLD, 4072, Australia.
  • Schuetz JD; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. john.schuetz@stjude.org.
Nat Commun ; 14(1): 5035, 2023 08 18.
Article en En | MEDLINE | ID: mdl-37596258
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transportadoras de Casetes de Unión a ATP / Alanina Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transportadoras de Casetes de Unión a ATP / Alanina Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article