Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease.
Curr Gastroenterol Rep
; 25(11): 316-322, 2023 Nov.
Article
en En
| MEDLINE
| ID: mdl-37646895
ABSTRACT
PURPOSE OF REVIEW Children with inflammatory bowel disease (IBD) are at increased risk of C. difficile infection (CDI) and experience worse outcomes associated with an infection. In this article, we review recent research on the incidence, diagnosis, complications, and treatment options for CDI in children with IBD. RECENT FINDINGS:
Children with IBD have an elevated incidence of CDI, but their CDI risk does not associate with established risk factors in adults with IBD. Existing testing methodologies are inadequate at differentiating CDI from C. difficile colonization in children with IBD. Fecal microbiota transplantation offers a durable cure for recurrent CDI. CDI remains a frequent occurrence in children with IBD. Careful clinical monitoring should be used to diagnose CDI and patients with co-occurring IBD and CDI require careful surveillance for worse outcomes. Future research should explore the optimal diagnosis and treatment modalities in this unique patient population.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Inflamatorias del Intestino
/
Clostridioides difficile
/
Infecciones por Clostridium
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Child
/
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article