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Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity.
Barbaraci, Carla; di Giacomo, Viviana; Maruca, Annalisa; Patamia, Vincenzo; Rocca, Roberta; Dichiara, Maria; Di Rienzo, Annalisa; Cacciatore, Ivana; Cataldi, Amelia; Balaha, Marwa; Rapino, Monica; Zagni, Chiara; Zampieri, Daniele; Pasquinucci, Lorella; Parenti, Carmela; Amata, Emanuele; Rescifina, Antonio; Alcaro, Stefano; Marrazzo, Agostino.
  • Barbaraci C; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • di Giacomo V; Department of Pharmacy, University "G. d'Annunzio", Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
  • Maruca A; Net4science academic spinoff srl, Università degli Studi "Magna Græcia" di Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Patamia V; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Rocca R; Net4science academic spinoff srl, Università degli Studi "Magna Græcia" di Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy.
  • Dichiara M; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Di Rienzo A; Department of Pharmacy, University "G. d'Annunzio", Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
  • Cacciatore I; Department of Pharmacy, University "G. d'Annunzio", Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
  • Cataldi A; Department of Pharmacy, University "G. d'Annunzio", Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
  • Balaha M; Department of Pharmacy, University "G. d'Annunzio", Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafr El Sheikh 33516, Egypt.
  • Rapino M; Genetic Molecular Institute of CNR, Unit of Chieti, "G. d' Annunzio" University, Via dei Vestini 31, 66100 Chieti-Pescara, Italy.
  • Zagni C; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Zampieri D; Department of Chemical and Pharmaceutical Sciences, University of Trieste, Via Giorgieri 1, 34127 Trieste, Italy.
  • Pasquinucci L; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Parenti C; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Amata E; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Rescifina A; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.
  • Alcaro S; Net4science academic spinoff srl, Università degli Studi "Magna Græcia" di Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro, Italy; Dipartimento di Scienze della Salute, Università degli Studi "Magna Græcia" di Catanzaro, Campus "Salvatore Venuta", Viale Europa, 88100, Catanzaro,
  • Marrazzo A; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy. Electronic address: marrazzo@unict.it.
Bioorg Chem ; 140: 106794, 2023 11.
Article en En | MEDLINE | ID: mdl-37659146
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article