Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation.

Shelke, Vishwadeep; Dagar, Neha; Gaikwad, Anil Bhanudas

Shelke, Vishwadeep; Dagar, Neha; Gaikwad, Anil Bhanudas.

Shelke V; Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Rajasthan 333031, India.
Dagar N; Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Rajasthan 333031, India.
Gaikwad AB; Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Rajasthan 333031, India. Electronic address: anil.gaikwad@pilani.bits-pilani.ac.in.

Life Sci ; 332: 122095, 2023 Nov 01.

Article en En | MEDLINE | ID: mdl-37722590

Asunto(s)

Lesión Renal Aguda; Diabetes Mellitus Experimental; Ratas; Masculino; Animales; Losartán/farmacología; Losartán/uso terapéutico; Receptor Toll-Like 4/metabolismo; Diabetes Mellitus Experimental/complicaciones; Diabetes Mellitus Experimental/tratamiento farmacológico; Ratas Wistar; Lesión Renal Aguda/etiología; Lesión Renal Aguda/inducido químicamente; Riñón/metabolismo; FN-kappa B/metabolismo; Inflamación/tratamiento farmacológico; Hipoxia/tratamiento farmacológico

Palabras clave

Acute kidney injury; Diabetes; Inflammation; Phloretin; Toll-like receptor 4

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Lesión Renal Aguda Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

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