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A precision-based exercise program for patients with multiple myeloma.
Dapunt, Ulrike; Ehret, Pauline; Paratte, Jean-Luc; Kuehl, Rea Maria; Wiskemann, Joachim; Jäger, Dirk; Müller-Tidow, Carsten; Raab, Marc-Steffen; Goldschmidt, Hartmut.
  • Dapunt U; GMMG-Study Group, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
  • Ehret P; GMMG-Study Group, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
  • Paratte JL; Working Group Exercise Oncology, Department of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University, Heidelberg, Germany.
  • Kuehl RM; Working Group Exercise Oncology, Department of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University, Heidelberg, Germany.
  • Wiskemann J; Working Group Exercise Oncology, Department of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University, Heidelberg, Germany.
  • Jäger D; Department of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University, Heidelberg, Germany.
  • Müller-Tidow C; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
  • Raab MS; Department of Internal Medicine V, Heidelberg Myeloma Center, Heidelberg University Hospital, Heidelberg, Germany.
  • Goldschmidt H; GMMG-Study Group, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
Eur J Haematol ; 111(6): 930-937, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37727991
ABSTRACT

OBJECTIVES:

Aim of this study was to retrospectively evaluate an interdisciplinary consultation followed by a precision-based exercise program (PEP) for myeloma patients with stable and unstable bone lesions.

METHODS:

Data of myeloma patients (n = 100) who received a PEP according to an orthopedic evaluation were analyzed. Bone stability was assessed by established scoring systems (Spinal Instability Neoplastic Score [SINS], Mirels' score). All patients with stable and unstable osteolyses received a PEP and n = 91 were contacted for a follow-up interview.

RESULTS:

In 60% of patients at least one osteolysis of the spine was considered potentially unstable or unstable. Following consultation, the number of patients performing resistance training could be significantly increased (≥2 sessions/week, 55%). Musculoskeletal pain was reported frequently. At the follow-up interview, 75% of patients who performed PEP stated that painful symptoms could be effectively alleviated by exercise. Moreover, only patients who exercised regularly discontinued pain medication. No injuries were reported in association with PEP.

CONCLUSION:

We were able to demonstrate that individualized resistance training is implementable and safe for myeloma patients. By means of a PEP, patients' self-efficacy in managing musculoskeletal pain was enhanced and pain medication could be reduced.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Dolor Musculoesquelético / Mieloma Múltiple Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Dolor Musculoesquelético / Mieloma Múltiple Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article