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Cell senescence, the senescence-associated secretory phenotype, and cancers.
Langhi Prata, Larissa G P; Tchkonia, Tamar; Kirkland, James L.
  • Langhi Prata LGP; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
PLoS Biol ; 21(9): e3002326, 2023 09.
Article en En | MEDLINE | ID: mdl-37733806
ABSTRACT
Cellular senescence is a cell fate caused by multiple stresses. A 2008 article in PLOS Biology reported a senescence-associated secretory phenotype that can promote inflammation and cancer, eventually enabling the development of senolytic drugs.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fenotipo Secretor Asociado a la Senescencia / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fenotipo Secretor Asociado a la Senescencia / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article