Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.

Wang, Hefei; He, Dewei; Li, Zhe; Gao, Xiyu; Yang, Shuo; Cui, Mingchi; Ye, Bojian; Huang, Bingxu; Fu, Shoupeng; Liu, Dianfeng

Wang, Hefei; He, Dewei; Li, Zhe; Gao, Xiyu; Yang, Shuo; Cui, Mingchi; Ye, Bojian; Huang, Bingxu; Fu, Shoupeng; Liu, Dianfeng.

Wang H; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: 15754346935@163.com.
He D; College of Animal Science, Jilin University, Changchun, China. Electronic address: m13144303829@163.com.
Li Z; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: lizhe9920@163.com.
Gao X; College of Animal Science, Jilin University, Changchun, China. Electronic address: xiyugdd@163.com.
Yang S; College of Animal Science, Jilin University, Changchun, China. Electronic address: 15204461165@163.com.
Cui M; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: 17649607145@163.com.
Ye B; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: yebj871781602@163.com.
Huang B; College of Animal Science, Jilin University, Changchun, China. Electronic address: huangbx16@mails.jlu.edu.cn.
Fu S; College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address: fushoupeng@jlu.edu.cn.
Liu D; College of Animal Science, Jilin University, Changchun, China. Electronic address: ccldf@163.com.

Chem Biol Interact ; 384: 110726, 2023 Oct 01.

Article en En | MEDLINE | ID: mdl-37741537

Asunto(s)

Fármacos Neuroprotectores; Enfermedad de Parkinson; Ratones; Animales; Enfermedad de Parkinson/metabolismo; Enfermedades Neuroinflamatorias; 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina/metabolismo; 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina/farmacología; 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina/uso terapéutico; FN-kappa B/metabolismo; 1-Metil-4-fenilpiridinio; Administración Oral; Ratones Endogámicos C57BL; Modelos Animales de Enfermedad; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Fármacos Neuroprotectores/metabolismo; Microglía; Neuronas Dopaminérgicas; Mamíferos/metabolismo

Palabras clave

AMPK/mTOR; Neuroinflammation; Neuroprotection; Parkinson's disease; Sophoricoside

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Fármacos Neuroprotectores Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

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