[<sup>225</sup>Ac]Ac- and [<sup>111</sup>In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts.

Kondo, Misaki; Cai, Zhongli; Chan, Conrad; Forkan, Nubaira; Reilly, Raymond M

[²²⁵Ac]Ac- and [¹¹¹In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts.

Kondo, Misaki; Cai, Zhongli; Chan, Conrad; Forkan, Nubaira; Reilly, Raymond M.

Kondo M; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Cai Z; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Chan C; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Forkan N; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Reilly RM; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada. raymond.reilly@utoronto.ca.

EJNMMI Radiopharm Chem ; 8(1): 24, 2023 Sep 26.

Article en En | MEDLINE | ID: mdl-37750937