Mesenchymal stem cell-derived exosomal miR-548x-3p inhibits pyroptosis of vascular endothelial cells through HMGB1 in heat stroke.

Pei, Yanfang; Ma, Wenfeng; Wang, Huifang; Chen, Fang; Xiao, Weiwei; Fan, Maiying; Han, Xiaotong; Cao, Yan

Pei, Yanfang; Ma, Wenfeng; Wang, Huifang; Chen, Fang; Xiao, Weiwei; Fan, Maiying; Han, Xiaotong; Cao, Yan.

Pei Y; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Ma W; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Wang H; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Chen F; Institute of Emergency Medicine, Hunan Provincial Key Laboratory of Emergency and Critical Care Metabonomics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Xiao W; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Fan M; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Han X; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Cao Y; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China. Electronic address: caoyan@hunnu.edu.cn.

Genomics ; 115(6): 110719, 2023 Nov.

Article en En | MEDLINE | ID: mdl-37757977

Asunto(s)

Proteína HMGB1; Golpe de Calor; Células Madre Mesenquimatosas; MicroARNs; Animales; Humanos; Ratones; Proteína HMGB1/genética; Células Endoteliales de la Vena Umbilical Humana; MicroARNs/genética; Proteína con Dominio Pirina 3 de la Familia NLR/genética; Piroptosis

Palabras clave

HMGB1; Heat stroke; Human bone marrow mesenchymal stem cells; Pyroptosis; miR-548x-3p

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Golpe de Calor / Proteína HMGB1 / MicroARNs / Células Madre Mesenquimatosas Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

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