RNA-Based Strategies for Cancer Therapy: In Silico Design and Evaluation of ASOs for Targeted Exon Skipping.

Pacelli, Chiara; Rossi, Alice; Milella, Michele; Colombo, Teresa; Le Pera, Loredana

Pacelli, Chiara; Rossi, Alice; Milella, Michele; Colombo, Teresa; Le Pera, Loredana.

Pacelli C; Department of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.
Rossi A; Section of Oncology, Department of Medicine, University of Verona-School of Medicine and Verona University Hospital Trust, 37134 Verona, Italy.
Milella M; Section of Oncology, Department of Medicine, University of Verona-School of Medicine and Verona University Hospital Trust, 37134 Verona, Italy.
Colombo T; Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), 00185 Rome, Italy.
Le Pera L; Core Facilities, Italian National Institute of Health (ISS), 00161 Rome, Italy.

Int J Mol Sci ; 24(19)2023 Oct 03.

Article en En | MEDLINE | ID: mdl-37834310

Asunto(s)

Neoplasias; Oligonucleótidos Antisentido; Humanos; Oligonucleótidos Antisentido/genética; Oligonucleótidos Antisentido/uso terapéutico; ARN; Neoplasias/terapia; Neoplasias/tratamiento farmacológico; Empalme del ARN; Exones/genética

Palabras clave

ASO; RNA therapy; antisense oligonucleotide; bioinformatics; cancer; splicing; targeted exon skipping

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligonucleótidos Antisentido / Neoplasias Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligonucleótidos Antisentido / Neoplasias Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article