Licochalcone A alleviates abnormal glucolipid metabolism and restores energy homeostasis in diet-induced diabetic mice.

Wang, Doudou; Yang, Lin; Ding, Wenwen; Chen, Ziyi; Yang, Xiaoxue; Jiang, Yu; Liu, Ying

Wang, Doudou; Yang, Lin; Ding, Wenwen; Chen, Ziyi; Yang, Xiaoxue; Jiang, Yu; Liu, Ying.

Wang D; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Yang L; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Ding W; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Chen Z; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Yang X; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Jiang Y; Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Liu Y; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.

Phytother Res ; 38(1): 196-213, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37850242

Asunto(s)

Chalconas; Diabetes Mellitus Experimental; Resistencia a la Insulina; Ratones; Animales; Chalconas/farmacología; Diabetes Mellitus Experimental/tratamiento farmacológico; Diabetes Mellitus Experimental/metabolismo; Dieta Alta en Grasa/efectos adversos; Homeostasis; Hígado; Ratones Endogámicos C57BL; Proteínas Quinasas Activadas por AMP/metabolismo; Metabolismo Energético; Mamíferos/metabolismo

Palabras clave

AMPK; licochalcone A; mTORC1; mitochondrial functions; type 2 diabetes mellitus

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Chalconas / Diabetes Mellitus Experimental Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

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