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Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind, active-controlled trial in Guinea and Sierra Leone.
Choi, Edward Man-Lik; Lacarra, Boris; Afolabi, Muhammed O; Ale, Boni Maxime; Baiden, Frank; Bétard, Christine; Foster, Julie; Hamzé, Benjamin; Schwimmer, Christine; Manno, Daniela; D'Ortenzio, Eric; Ishola, David; Keita, Cheick Mohamed; Keshinro, Babajide; Njie, Yusupha; van Dijck, Wim; Gaddah, Auguste; Anumendem, Dickson; Lowe, Brett; Vatrinet, Renaud; Lawal, Bolarinde Joseph; Otieno, Godfrey T; Samai, Mohamed; Deen, Gibrilla Fadlu; Swaray, Ibrahim Bob; Kamara, Abu Bakarr; Kamara, Michael Morlai; Diagne, Mame Aminata; Kowuor, Dickens; McLean, Chelsea; Leigh, Bailah; Beavogui, Abdoul Habib; Leyssen, Maarten; Luhn, Kerstin; Robinson, Cynthia; Douoguih, Macaya; Greenwood, Brian; Thiébaut, Rodolphe; Watson-Jones, Deborah.
  • Choi EM; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK. Electronic address: edward.choi@lshtm.ac.uk.
  • Lacarra B; REACTing Unit, Inserm, Paris, France.
  • Afolabi MO; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • Ale BM; Clinical Investigation Center-Clinical Epidemiology, University of Bordeaux, Inserm, Institut Bergonié, EUCLID/F-CRIN CIC-EC1401, Bordeaux, France.
  • Baiden F; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • Bétard C; Clinical Investigation Center-Clinical Epidemiology, University of Bordeaux, Inserm, Institut Bergonié, EUCLID/F-CRIN CIC-EC1401, Bordeaux, France.
  • Foster J; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
  • Hamzé B; Pôle Recherche Clinique, Inserm, Paris, France.
  • Schwimmer C; Clinical Investigation Center-Clinical Epidemiology, University of Bordeaux, Inserm, Institut Bergonié, EUCLID/F-CRIN CIC-EC1401, Bordeaux, France; Department of Medical Information, Centre Hospitalier Universitaire (CHU) de Bordeaux, EUCLID/F-CRIN CIC-EC1401, Inserm, Institut Bergonié, Bordeaux, Fr
  • Manno D; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
  • D'Ortenzio E; ANRS, Maladies infectieuses émergentes, Inserm, Paris, France.
  • Ishola D; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • Keita CM; Centre National de Formation et de Recherche en Santé Rurale de Mafèrinyah, Forécariah, Guinea.
  • Keshinro B; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Njie Y; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • van Dijck W; Janssen Research & Development, Beerse, Belgium.
  • Gaddah A; Janssen Research & Development, Beerse, Belgium.
  • Anumendem D; Janssen Research & Development, Beerse, Belgium.
  • Lowe B; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
  • Vatrinet R; REACTing Unit, Inserm, Paris, France.
  • Lawal BJ; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • Otieno GT; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; EBOVAC-Salone Project, Kambia, Sierra Leone.
  • Samai M; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
  • Deen GF; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
  • Swaray IB; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
  • Kamara AB; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
  • Kamara MM; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
  • Diagne MA; Laboratoire de Sociologie, Anthropologie et Psychologie Sociale, Department of Sociology, Université Cheikh Anta Diop de Dakar, Dakar, Senegal.
  • Kowuor D; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
  • McLean C; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Leigh B; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
  • Beavogui AH; Centre National de Formation et de Recherche en Santé Rurale de Mafèrinyah, Forécariah, Guinea.
  • Leyssen M; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Luhn K; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Robinson C; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Douoguih M; Janssen Vaccines & Prevention, Leiden, Netherlands.
  • Greenwood B; Department of Disease Control, London School of Hygiene & Tropical Medicine, London, UK.
  • Thiébaut R; Clinical Investigation Center-Clinical Epidemiology, University of Bordeaux, Inserm, Institut Bergonié, EUCLID/F-CRIN CIC-EC1401, Bordeaux, France; Department of Medical Information, Centre Hospitalier Universitaire (CHU) de Bordeaux, EUCLID/F-CRIN CIC-EC1401, Inserm, Institut Bergonié, Bordeaux, Fr
  • Watson-Jones D; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; Mwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania.
Lancet Glob Health ; 11(11): e1743-e1752, 2023 11.
Article en En | MEDLINE | ID: mdl-37858585
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Ebolavirus Límite: Animals / Humans / Infant País como asunto: Africa Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Ebolavirus Límite: Animals / Humans / Infant País como asunto: Africa Idioma: En Año: 2023 Tipo del documento: Article