Distinct mechanisms drive sequential internalization and degradation of GABA<sub>A</sub>Rs during global ischemia and reperfusion injury.

Distinct mechanisms drive sequential internalization and degradation of GABA_ARs during global ischemia and reperfusion injury.

Garcia, Joshua D; Wolfe, Sarah E; Stewart, Amber R; Tiemeier, Erika; Gookin, Sara E; Guerrero, Mayra Bueno; Quillinan, Nidia; Smith, Katharine R.

Garcia JD; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Wolfe SE; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Stewart AR; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Tiemeier E; Department of Anesthesiology, Neuronal Injury Program, University of Colorado School of Medicine, Anschutz Medical Campus, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Gookin SE; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Guerrero MB; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.
Quillinan N; Department of Anesthesiology, Neuronal Injury Program, University of Colorado School of Medicine, Anschutz Medical Campus, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Smith KR; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 East 19th Avenue, Aurora, CO 80045, USA.

iScience ; 26(10): 108061, 2023 Oct 20.

Article en En | MEDLINE | ID: mdl-37860758