ASH2L-mediated H3K4me3 drives diabetic nephropathy through HIPK2 and Notch1 pathway.

Zhong, Wen; Hong, Chen; Zhang, Yuyu; Li, Yuhui; Xiao, Chenxi; Liu, Xinhua

Zhong, Wen; Hong, Chen; Zhang, Yuyu; Li, Yuhui; Xiao, Chenxi; Liu, Xinhua.

Zhong W; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China.
Hong C; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China.
Zhang Y; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China.
Li Y; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China.
Xiao C; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China.
Liu X; Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai 201203, China. Electronic address: liuxinhua@fudan.edu.cn.

Transl Res ; 264: 85-96, 2024 02.

Article en En | MEDLINE | ID: mdl-37879562

Asunto(s)

Diabetes Mellitus; Nefropatías Diabéticas; Histonas; Hiperglucemia; Animales; Ratones; Diabetes Mellitus/patología; Nefropatías Diabéticas/tratamiento farmacológico; Fibrosis; Hiperglucemia/metabolismo; Inflamación/patología; Riñón/patología

Palabras clave

ADAM17; ASH2L; Diabetic nephropathy; HIPK2; NICD1

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Diabetes Mellitus / Nefropatías Diabéticas / Hiperglucemia Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google