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Insights into the molecular basis and mechanism of heme-triggered TLR4 signalling: The role of heme-binding motifs in TLR4 and MD2.
Hopp, Marie-T; Holze, Janine; Lauber, Felicitas; Holtkamp, Laura; Rathod, Dhruv C; Miteva, Maria A; Prestes, Elisa B; Geyer, Matthias; Manoury, Bénédicte; Merle, Nicolas S; Roumenina, Lubka T; Bozza, Marcelo T; Weindl, Günther; Imhof, Diana.
  • Hopp MT; Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
  • Holze J; Department of Chemistry, Institute of Integrated Natural Sciences, University of Koblenz, Koblenz, Germany.
  • Lauber F; Pharmacology and Toxicology, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
  • Holtkamp L; Pharmacology and Toxicology, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
  • Rathod DC; Pharmacology and Toxicology, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
  • Miteva MA; Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, Bonn, Germany.
  • Prestes EB; CNRS UMR 8038 CiTCoM, Université de Paris, Faculté de Pharmacie de Paris, Paris, France.
  • Geyer M; INSERM U 1268 Medicinal Chemistry and Translational Research, Paris, France.
  • Manoury B; Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
  • Merle NS; Institute of Structural Biology, University of Bonn, Bonn, Germany.
  • Roumenina LT; Institut Necker Enfants Malades, INSERM U1151-CNRS UMR8253, Université Paris Cité, Faculté de médecine Necker, Paris, France.
  • Bozza MT; Centre de Recherche des Cordeliers, UMR_S 1138, INSERM, Paris, France.
  • Weindl G; Centre de Recherche des Cordeliers, Sorbonne Universités, Paris, France.
  • Imhof D; Centre de Recherche des Cordeliers, Université Paris Descartes, Paris, France.
Immunology ; 171(2): 181-197, 2024 Feb.
Article en En | MEDLINE | ID: mdl-37885279
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor Toll-Like 4 Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Receptor Toll-Like 4 Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article