Glycine-Alanine Dipeptide Repeat Protein from C9-ALS Interacts with Sulfide Quinone Oxidoreductase (SQOR) to Induce the Activity of the NLRP3 Inflammasome in HMC3 Microglia: Irisflorentin Reverses This Interaction.

Fu, Ru-Huei; Chen, Hui-Jye; Hong, Syuan-Yu

Fu, Ru-Huei; Chen, Hui-Jye; Hong, Syuan-Yu.

Fu RH; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Chen HJ; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Hong SY; Ph.D. Program for Aging, China Medical University, Taichung 40402, Taiwan.

Antioxidants (Basel) ; 12(10)2023 Oct 23.

Article en En | MEDLINE | ID: mdl-37891975

Palabras clave

C9ORF72; NLRP3 inflammasome; ROS; amyotrophic lateral sclerosis (ALS); glycine-alanine dipeptide repeat proteins (GA-DPRs); irisflorentin; mitochondria DNA; sulfide quinone oxidoreductase (SQOR)

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2023 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2023 Tipo del documento: Article