Molecular prevalence of Pneumocystis jirovecii and Cryptosporidium in patients with asthma.
Diagn Microbiol Infect Dis
; 108(1): 116124, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-37913698
ABSTRACT
Asthma is characterized by chronic airway inflammation. In addition to allergens, microorganisms can affect the clinical course of asthma. It has been shown that some fungi play an important role in the progression of asthma. However, the effects of Pneumocystis jirovecii and Cryptosporidium spp., on the disease are little known. We investigated P. jirovecii and Cryptosporidium spp. in the sputum and stool sample of patients with asthma (n = 40) by microscopy and PCR compared to the healthy group (n = 40). P. jirovecii (12.5 %), and Cryptosporidium spp. (12.5 %) were detected in the sputum samples of only asthmatic patients (p = 0.029 and 0.029 respectively). However, Crpytosporidium spp. was detected equally in stool samples of both groups (p = 0.682). Our results indicate that P. jirovecii and Cryptosporidium spp. should be considered in patients with asthma and molecular screening of these neglected eukaryotes in respiratory tract samples may be beneficial in the clinical management of the disease.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neumonía por Pneumocystis
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Asma
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Criptosporidiosis
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Cryptosporidium
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Pneumocystis carinii
Límite:
Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article