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Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Streblow, Daniel N; Hirsch, Alec J; Stanton, Jeffrey J; Lewis, Anne D; Colgin, Lois; Hessell, Ann J; Kreklywich, Craig N; Smith, Jessica L; Sutton, William F; Chauvin, David; Woo, Jennifer; Bimber, Benjamin N; LeBlanc, Cierra N; Acharya, Sonia N; O'Roak, Brian J; Sardar, Harjinder; Sajadi, Mohammad M; Tehrani, Zahra R; Walter, Mark R; Martinez-Sobrido, Luis; Kobie, James J; Reader, Rachel J; Olstad, Katherine J; Hobbs, Theodore R; Saphire, Erica Ollmann; Schendel, Sharon L; Carnahan, Robert H; Knoch, Jonas; Branco, Luis M; Crowe, James E; Van Rompay, Koen K A; Lovalenti, Phillip; Forthal, Donald N; Haigwood, Nancy L.
  • Streblow DN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  • Hirsch AJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  • Stanton JJ; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Lewis AD; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Colgin L; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Hessell AJ; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Kreklywich CN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  • Smith JL; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  • Sutton WF; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Chauvin D; Aridis Pharmaceuticals, Los Gatos, CA, USA.
  • Woo J; Aridis Pharmaceuticals, Los Gatos, CA, USA.
  • Bimber BN; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • LeBlanc CN; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Acharya SN; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • O'Roak BJ; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Sardar H; Environmental Health & Safety, Oregon Health & Science University, Portland, OR, USA.
  • Sajadi MM; Baltimore VA Medical Center, VA Maryland Health Care System, Baltimore, MD, USA.
  • Tehrani ZR; Division of Clinical Care and Research, Institute of Human Virology, University of Maryland, Baltimore, MD, USA.
  • Walter MR; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Kobie JJ; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Reader RJ; California National Primate Research Center, University of California, Davis, CA, USA.
  • Olstad KJ; California National Primate Research Center, University of California, Davis, CA, USA.
  • Hobbs TR; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Saphire EO; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Schendel SL; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Carnahan RH; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Knoch J; PARI Pharma GmbH, Starnberg, Germany.
  • Branco LM; Zalgen Labs, LLC, Frederick, MD, USA.
  • Crowe JE; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Van Rompay KKA; California National Primate Research Center, University of California, Davis, CA, USA.
  • Lovalenti P; Aridis Pharmaceuticals, Los Gatos, CA, USA.
  • Vu Truong; Aridis Pharmaceuticals, Los Gatos, CA, USA. truongv@aridispharma.com.
  • Forthal DN; University of California, Irvine, School of Medicine, Irvine, CA, USA. dnfortha@hs.uci.edu.
  • Haigwood NL; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA. haigwoon@ohsu.edu.
Nat Commun ; 14(1): 7062, 2023 11 03.
Article en En | MEDLINE | ID: mdl-37923717
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article