Silencing of GDF11 suppresses hepatocyte apoptosis to relieve LPS/D-GalN acute liver failure.

Zhou, Rongsheng; Li, Shuang; Wang, Qun; Bi, Yang; Li, Xiaogang; Wang, Qiang

Zhou, Rongsheng; Li, Shuang; Wang, Qun; Bi, Yang; Li, Xiaogang; Wang, Qiang.

Zhou R; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li S; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang Q; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Bi Y; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li X; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang Q; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

J Biochem Mol Toxicol ; 38(1): e23577, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37934488

Asunto(s)

Lipopolisacáridos; Fallo Hepático Agudo; Animales; Ratones; Apoptosis; Hepatocitos; Lipopolisacáridos/toxicidad; Hígado/metabolismo; Fallo Hepático Agudo/inducido químicamente; Fallo Hepático Agudo/metabolismo; Fallo Hepático Agudo/patología; Mamíferos/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Serina-Treonina Quinasas TOR/metabolismo

Palabras clave

PI3K/Akt/mTOR signaling pathway: apoptosis; acute liver failure; growth differentiation factor-11; proliferation; recombinant adenovirus

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lipopolisacáridos / Fallo Hepático Agudo Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lipopolisacáridos / Fallo Hepático Agudo Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article