RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12.
Nucleic Acids Res
; 52(D1): D255-D264, 2024 Jan 05.
Article
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| MEDLINE
| ID: mdl-37971353
ABSTRACT
RegulonDB is a database that contains the most comprehensive corpus of knowledge of the regulation of transcription initiation of Escherichia coli K-12, including data from both classical molecular biology and high-throughput methodologies. Here, we describe biological advances since our last NAR paper of 2019. We explain the changes to satisfy FAIR requirements. We also present a full reconstruction of the RegulonDB computational infrastructure, which has significantly improved data storage, retrieval and accessibility and thus supports a more intuitive and user-friendly experience. The integration of graphical tools provides clear visual representations of genetic regulation data, facilitating data interpretation and knowledge integration. RegulonDB version 12.0 can be accessed at https//regulondb.ccg.unam.mx.
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1
Banco de datos:
MEDLINE
Asunto principal:
Regulación Bacteriana de la Expresión Génica
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Bases de Datos Genéticas
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Escherichia coli K12
Idioma:
En
Año:
2024
Tipo del documento:
Article