Antioxidant, anti-inflammatory, and anti-apoptotic effects of genkwanin against aflatoxin B<sub>1</sub>-induced testicular toxicity.

Ijaz, Muhammad Umar; Ishtiaq, Ayesha; Tahir, Arfa; Alvi, Mughees Aizaz; Rafique, Azhar; Wang, Peng; Zhu, Guo-Ping

Antioxidant, anti-inflammatory, and anti-apoptotic effects of genkwanin against aflatoxin B₁-induced testicular toxicity.

Ijaz, Muhammad Umar; Ishtiaq, Ayesha; Tahir, Arfa; Alvi, Mughees Aizaz; Rafique, Azhar; Wang, Peng; Zhu, Guo-Ping.

Ijaz MU; Department of Zoology, Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan. Electronic address: umar.ijaz@uaf.edu.pk.
Ishtiaq A; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases, Auhui Provincial Engineering Research Centre for Molecular Detection and Diagnostics, College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China.
Tahir A; Department of Zoology, Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan.
Alvi MA; Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan.
Rafique A; Department of Zoology, Government College University, Faisalabad, Pakistan.
Wang P; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases, Auhui Provincial Engineering Research Centre for Molecular Detection and Diagnostics, College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China.
Zhu GP; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases, Auhui Provincial Engineering Research Centre for Molecular Detection and Diagnostics, College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China. Electronic address: gpz2012@ahnu.edu.cn.

Toxicol Appl Pharmacol ; 481: 116750, 2023 12 15.

Article en En | MEDLINE | ID: mdl-37980962

Asunto(s)

Aflatoxina B1; Antioxidantes; Masculino; Ratas; Animales; Antioxidantes/farmacología; Antioxidantes/metabolismo; Aflatoxina B1/toxicidad; Aflatoxina B1/metabolismo; Proteína 1 Asociada A ECH Tipo Kelch/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; Semen/metabolismo; Estrés Oxidativo; Antiinflamatorios/farmacología

Palabras clave

Aflatoxin B(1); Antioxidant; Genkwanin; Nrf2/Keap1 pathway; Oxidative stress; Testicular damage

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aflatoxina B1 / Antioxidantes Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aflatoxina B1 / Antioxidantes Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article