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The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents.
Linciano, Pasquale; Pozzi, Cecilia; Tassone, Giusy; Landi, Giacomo; Mangani, Stefano; Santucci, Matteo; Luciani, Rosaria; Ferrari, Stefania; Santarem, Nuno; Tagliazucchi, Lorenzo; Cordeiro-da-Silva, Anabela; Tonelli, Michele; Tondi, Donatella; Bertarini, Laura; Gul, Sheraz; Witt, Gesa; Moraes, Carolina B; Costantino, Luca; Costi, Maria Paola.
  • Linciano P; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Pozzi C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, 53100, Siena, Italy; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugual.
  • Tassone G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, 53100, Siena, Italy.
  • Landi G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, 53100, Siena, Italy.
  • Mangani S; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, 53100, Siena, Italy.
  • Santucci M; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Luciani R; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Ferrari S; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Santarem N; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugual; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge ViterboFerreira 228, 4050-313 Porto, Portugal.
  • Tagliazucchi L; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy; Clinical and Experimental Medicine (CEM) PhD Program, University of Modena and Reggio Emilia, Via Campi 278, 41125, Modena, Italy.
  • Cordeiro-da-Silva A; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugual; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge ViterboFerreira 228, 4050-313 Porto, Portugal.
  • Tonelli M; Department of Pharmacy, University of Genoa, Viale Benedetto XV, 3, 16132, Genoa, Italy.
  • Tondi D; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Bertarini L; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Gul S; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Hamburg, Germany.
  • Witt G; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Hamburg, Germany.
  • Moraes CB; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), 13083-100, Campinas, SP, Brazil.
  • Costantino L; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.
  • Costi MP; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy. Electronic address: mariapaola.costi@unimore.it.
Eur J Med Chem ; 264: 115946, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38043491
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trypanosoma brucei brucei / Trypanosoma cruzi / Enfermedad de Chagas / Antiprotozoarios Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trypanosoma brucei brucei / Trypanosoma cruzi / Enfermedad de Chagas / Antiprotozoarios Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article