Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response.

Bhagchandani, Sachin H; Yang, Leerang; Maiorino, Laura; Ben-Akiva, Elana; Rodrigues, Kristen A; Romanov, Anna; Suh, Heikyung; Aung, Aereas; Wu, Shengwei; Wadhera, Anika; Chakraborty, Arup K; Irvine, Darrell J.

Bhagchandani SH; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Yang L; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Maiorino L; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Ben-Akiva E; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, U.S.A.
Rodrigues KA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, U.S.A.
Romanov A; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Suh H; Department of Physics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Aung A; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Wu S; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, U.S.A.
Wadhera A; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, U.S.A.
Chakraborty AK; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, U.S.A.
Irvine DJ; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

bioRxiv ; 2023 Nov 21.

Article en En | MEDLINE | ID: mdl-38045401

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2023 Tipo del documento: Article