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Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation.
Dijkstra, Douwe J; van de Bovenkamp, Fleur S; Abendstein, Leoni; Zuijderduijn, Rob; Pool, Jos; Kramer, Cynthia S M; Slot, Linda M; Drijfhout, Jan W; de Vor, Lisanne; Gelderman, Kyra A; Rooijakkers, Suzan H M; Zaldumbide, Arnaud; Vidarsson, Gestur; Sharp, Thomas H; Parren, Paul W H I; Trouw, Leendert A.
  • Dijkstra DJ; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • van de Bovenkamp FS; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Abendstein L; Lava Therapeutics, Utrecht 3584 CM, The Netherlands.
  • Zuijderduijn R; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Pool J; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Kramer CSM; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Slot LM; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Drijfhout JW; Department of Rheumatology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • de Vor L; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Gelderman KA; Department of Medical Microbiology, University Medical Center, Utrecht 3584 CX, The Netherlands.
  • Rooijakkers SHM; Sanquin Diagnostic Services, Amsterdam 1066 CX, The Netherlands.
  • Zaldumbide A; Department of Medical Microbiology, University Medical Center, Utrecht 3584 CX, The Netherlands.
  • Vidarsson G; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Sharp TH; Department of Experimental Immunohematology, Sanquin Research, Amsterdam 1066 CX, The Netherlands.
  • Parren PWHI; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
  • Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
Proc Natl Acad Sci U S A ; 120(50): e2310666120, 2023 Dec 12.
Article en En | MEDLINE | ID: mdl-38048459
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Lupus Eritematoso Sistémico Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Lupus Eritematoso Sistémico Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article