PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site.

Ryan, Christine B; Choi, James S; Kang, Brian; Herr, Seth; Pereira, Claudia; Moraes, Carlos T; Al-Ali, Hassan; Lee, Jae K

Ryan, Christine B; Choi, James S; Kang, Brian; Herr, Seth; Pereira, Claudia; Moraes, Carlos T; Al-Ali, Hassan; Lee, Jae K.

Ryan CB; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America.
Choi JS; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America.
Kang B; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America.
Herr S; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America.
Pereira C; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, United States of America.
Moraes CT; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, United States of America.
Al-Ali H; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America; Department of Medicine Katz Division of Nephrology and Hypertension, University of Miami, Miller School of Medicine, Miami, FL, United States
Lee JK; Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States of America. Electronic address: JLee22@med.miami.edu.

Neurobiol Dis ; 190: 106370, 2024 Jan.

Article en En | MEDLINE | ID: mdl-38049013

Asunto(s)

Fosfatidilinositol 3-Quinasas; Traumatismos de la Médula Espinal; Ratones; Animales; Fosfatidilinositol 3-Quinasas/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Macrófagos/metabolismo; Traumatismos de la Médula Espinal/metabolismo; Lípidos; Médula Espinal/patología

Palabras clave

Autophagy; Foamy macrophages; Lipids; Neuroinflammation; PI3K; Spinal cord injury

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Traumatismos de la Médula Espinal / Fosfatidilinositol 3-Quinasas Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

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