Systematic review of reverse vaccinology and immunoinformatics data for non-viral sexually transmitted infections.
An Acad Bras Cienc
; 95(suppl 2): e20230617, 2023.
Article
en En
| MEDLINE
| ID: mdl-38055447
ABSTRACT
Sexually Transmitted Infections (STIs) are a public health burden rising in developed and developing nations. The World Health Organization estimates nearly 374 million new cases of curable STIs yearly. Global efforts to control their spread have been insufficient in fulfilling their objective. As there is no vaccine for many of these infections, these efforts are focused on education and condom distribution. The development of vaccines for STIs is vital for successfully halting their spread. The field of immunoinformatics is a powerful new tool for vaccine development, allowing for the identification of vaccine candidates within a bacterium's genome and allowing for the design of new genome-based vaccine peptides. The goal of this review was to evaluate the usage of immunoinformatics in research focused on non-viral STIs, identifying fields where research efforts are concentrated. Here we describe gaps in applying these techniques, as in the case of Treponema pallidum and Trichomonas vaginalis.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Trichomonas vaginalis
/
Vacunas
/
Enfermedades de Transmisión Sexual
Tipo de estudio:
Systematic_reviews
Límite:
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article