An oncogenic phenoscape of colonic stem cell polarization.

Qin, Xiao; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; Claus, Jeroen; Tape, Christopher J

Qin, Xiao; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; Claus, Jeroen; Tape, Christopher J.

Qin X; Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Cardoso Rodriguez F; Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Sufi J; Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Vlckova P; Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Claus J; Phospho Biomedical Animation, The Greenhouse Studio 6, London N17 9QU, UK.
Tape CJ; Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK. Electronic address: c.tape@ucl.ac.uk.

Cell ; 186(25): 5554-5568.e18, 2023 12 07.

Article en En | MEDLINE | ID: mdl-38065080

Asunto(s)

Proteínas Proto-Oncogénicas p21(ras); Transducción de Señal; Diferenciación Celular; Oncogenes; Proteínas Proto-Oncogénicas p21(ras)/genética; Células Madre; Humanos; Animales; Ratones; Linaje de la Célula

Palabras clave

CRC; cell plasticity; cell-cell signaling; cell-fate polarization; colonic stem cell; colorectal cancer; cue-signal-response; organoid; single-cell analysis; tumor microenvironment

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Proto-Oncogénicas p21(ras) Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

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