Genetic insights into the association of statin and newer nonstatin drug target genes with human longevity: a Mendelian randomization analysis.

Chen, Han; Zhou, Xiaoying; Hu, Jingwen; Li, Shuo; Wang, Zi; Zhu, Tong; Cheng, Hong; Zhang, Guoxin

Chen, Han; Zhou, Xiaoying; Hu, Jingwen; Li, Shuo; Wang, Zi; Zhu, Tong; Cheng, Hong; Zhang, Guoxin.

Chen H; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou Road, Nanjing, 210029, People's Republic of China. chenhan0688@njmu.edu.cn.
Zhou X; Branch of Health Promotion and Education, Jiangsu Anti-aging Association, Nanjing, People's Republic of China. chenhan0688@njmu.edu.cn.
Hu J; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou Road, Nanjing, 210029, People's Republic of China.
Li S; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Wang Z; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou Road, Nanjing, 210029, People's Republic of China.
Zhu T; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou Road, Nanjing, 210029, People's Republic of China.
Cheng H; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Zhang G; Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.

Lipids Health Dis ; 22(1): 220, 2023 Dec 12.

Article en En | MEDLINE | ID: mdl-38082436

Asunto(s)

Inhibidores de Hidroximetilglutaril-CoA Reductasas; Humanos; Inhibidores de Hidroximetilglutaril-CoA Reductasas/farmacología; Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico; Proproteína Convertasa 9/genética; Longevidad/genética; Análisis de la Aleatorización Mendeliana; Estudio de Asociación del Genoma Completo; LDL-Colesterol; Apolipoproteínas B; Proteína 3 Similar a la Angiopoyetina

Palabras clave

APOC3; CETP; Drug-target Mendelian randomization; Human longevity; LDLR

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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