Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within the mobilome through advanced comparative analysis.
Microbiol Spectr
; 12(1): e0196423, 2024 Jan 11.
Article
en En
| MEDLINE
| ID: mdl-38099617
ABSTRACT
Horizontal gene transfer (HGT) is a key driver in the evolution of bacterial genomes. The acquisition of genes mediated by HGT may enable bacteria to adapt to ever-changing environmental conditions. Long-term application of antibiotics in intensive agriculture is associated with the dissemination of antibiotic resistance genes among bacteria with the consequences causing public health concern. Commensal farm-animal-associated gut microbiota are considered the reservoir of the resistance genes. Therefore, in this study, we identified known and not-yet characterized mobilized genes originating from chicken and porcine fecal samples using our innovative pipeline followed by network analysis to provide appropriate visualization to support proper interpretation.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Transferencia de Gen Horizontal
/
Microbiota
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article