Diterpenoid Alkaloids from Delphinium ajacis and Their Anti-inflammatory Activity.
Chem Biodivers
; 21(2): e202301958, 2024 Feb.
Article
en En
| MEDLINE
| ID: mdl-38130145
ABSTRACT
Three novel diterpenoid alkaloids, comprising two C19 -diterpenoid alkaloids (1 and 2) and one C20 -diterpenoid alkaloid (3), were isolated from Delphinium ajacis, alongside the six known compoundsâ
(4-9). Their structures were elucidated by spectroscopic methods (MS, UV, IR, 1D and 2D NMR) and chemical properties. Simultaneously, the anti-inflammatory properties of all compoundsâ
(1-9) was conducted, focusing on nitric oxide (NO) production in LPS-induced BV-2 cells. The results indicated compoundsâ
1-3, 7, and 8 have potential anti-inflammatory activity.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Delphinium
/
Diterpenos
/
Alcaloides
Idioma:
En
Año:
2024
Tipo del documento:
Article